provironas,klostilbegitas,tamoksifenas,nolvadeksas ,arimideksas

[7nickas]

Proviron

Pharmacology is the study of drugs and their effects. Anabolic Pharmacology is the study of drugs that have a growth promoting effect in muscle. This column will explore Anabolic Pharmacology by profiling a different anabolic drug and its effects each month. The focus of discussion this month will be the anabolic androgenic steroid, Proviron:

Mesterolone is a simple derivative of dihydrotestosterone and is commonly known by its trade name, Proviron. The addition of a methyl group to the 1 position, like methenolone, should help to provide a small amount of protection from metabolism when taken orally. In fact the only difference between methenolone and mesterolone is the presence of a double bond in the 1,2 position with methenolone. This double bond changes the shape of the A-ring as well as the location of the 1-methyl group. Though these drugs are so similar in appearance, they are quite different in activity. While the 1-methyl and 1-double bond help to keep methenolone from being metabolized to inactive metabolites, the presence of only a 1 methyl group seems to provide mesterolone with little protection and it is likely deactivated quickly.

Since mesterolone is already 5-alpha reduced, it is not subject to further metabolism by 5-alpha reductase. Mesterolone, as a DHT-derivative, cannot be converted by aromatase to estrogenic metabolites and has some degree of inhibition of aromatase and likely some inhibition of 5-alpha reductase as well. In fact, many consider mesterolone to be an anti-estrogen, and its use in the literature seems to support this to some degree. Mesterolone is one of the strongest binder of SHBG commercially available, in fact, only DHT binds to SHBG more strongly1,2. As discussed earlier, SHBG plays a very important role in testosterone metabolism. Because mesterolone binds so strongly to SHBG it tends to bump other less strongly bound molecules in the “free” state where they can bind the androgen receptor3. Therefore, some athletes have attempted to use mesterolone for this purpose. They add mesterolone to a cycle if the hopes that more steroid will remain free and active. This would also be true for testosterone and estrogen.

Mesterolone would be capable of bumping both of these hormones into circulation as well which may result in androgenic or estrogenic effects. There is no evidence that mesterolone binds to glucocorticoid or progesterone receptors. Mesterolone is not known for being very anabolic even though the anabolic to androgenic ratio when given subcutaneously is favorable. When given orally, mesterolone undergoes significant metabolism that greatly reduces any anabolic effect4. The fact that mesterolone has been shown to have little effect on red blood cell production, unlike other androgens, seems to confirm its rapid metabolism5. Mesterolone has been studied quite extensively in the literature as a fertility treatment to increase sperm quantity. There is quite a bit of conflicting data showing mesterolone to have variable effects on LH and FSH, though it is generally been shown to not reduce normal levels of LH and FSH6. Though its use as an SHBG binder is somewhat questionable, it may have use in blocking the metabolism of other DHT derivatives by 3-alpha hydroxysteroid dehydrogenase since it seems to have significant affinity for this enzyme.

[Abladoras]

Kur galma isigyti provirono ? ir ka patartumet po mini decos kurso ?

[bodybuilding]

kaip taisyklingiausia vartot tamoxifena po kurso?

[sliosas]

Originaliai Išsiųstas Abladoras

Kur galma isigyti provirono ? ir ka patartumet po mini decos kurso ?

nesu girdejas kad yra mini dekos kursas kiek laiko jis trunka?

[triumfass]

buna dekos kursai be dekos

[fine]

gal ir keistas klausimas, bet noriu paklausti, vartojant provirona po kurso, vartoti kreatino monohidrata, ar geriau palaukti kol nebus vartojamas proviron?

[extremasss]

kaip nori.

[ro_mka]

Originaliai Išsiųstas bodybuilding

kaip taisyklingiausia vartot tamoxifena po kurso?

ka turi omeny kaip taisyklingiau? po viena tablete per diena 3-4sav, ir visos taisykles.

[1qaz]

koki PCT reikia daryti po 6 sav kurso
masteron, propiko, vinstrolio(injekcinio arba tab.) 100mg eod
ir 600mg boldenon i savaite?

[ro_mka]

Originaliai Išsiųstas 1qaz

koki PCT reikia daryti po 6 sav kurso
masteron, propiko, vinstrolio(injekcinio arba tab.) 100mg eod
ir 600mg boldenon i savaite?

pirmiausiai tai testosterona ilgiau palaikyt bent pora savaiciu reiketu jei bolda 6 savaites laikei. o po to jau nuo to pct priklauso.